????? ??? ???? ???? ???, ?? ???? ??? ???? ????. ??? ????? ??? ????, ??? ??? ??? ????. ????? ?????? ??? ??? ???? ???, ??? ?? ??? ??? ????? ??? ??? ? ??? ??? ?? ??? ?????. ??, ???? ??? ???? ??? ??? ? ? ????. ????? one of the most serious risk factors is ????? ???? ?? ???? ???. ??? ??? ???? ?? ?????